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Tuesday, June 14, 2011

Guna rahim ibu sendiri untuk cuba hamil

Eva and Sara Ottosson could be involved in a transplant first.

Eva and Sara Ottosson could be involved in a transplant first.

A British woman is preparing to become the first person in the world to have her womb transplanted into her daughter.

Eva Ottosson, 56, has agreed to take part in a groundbreaking medical procedure, which, if successful, could see her donate her uterus to her 25-year-old daughter, Sara.

Doctors hope that if the transplant is successful, Sara, who was born without reproductive organs, could become pregnant and carry a child in the same womb from which she herself was born.
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It is hoped the complex transplant operation could take place as early as next northern spring in Sweden, where doctors in Gothenburg have been assessing suitable patients for the revolutionary procedure.

Mrs Ottosson, who runs a lighting business in Nottingham, said: ''My daughter and I are both very rational people and we both think 'it's just a womb'.

''She needs the womb and if I'm the best donor for her, well, go on. She needs it more than me. I've had two daughters so it's served me well.''

Sara and her mother are among a small group chosen to take part in the program. They have undergone tests and are waiting to hear if they will be the first to have the procedure.

The only previous womb transplant took place in Saudi Arabia in 2000 when a 26-year-old woman, who had lost her uterus due to a haemorrhage, received a womb from a 46-year-old. However, the recipient developed problems and the womb had to be removed after 99 days.

Since then, medical knowledge of the surgical procedure has improved and a team in Gothenburg believe they are at the stage where they can perform a successful transplant.

Sara, who lives and works in Stockholm, has a condition called Mayer Rokitansky Kuster Hauser (MRKH) syndrome, which affects about one in 5000 women, and means she was born without a uterus and some parts of the vagina.

The cause is unknown but, like many women with the condition, Sara only realised she was missing her reproductive organs when she was a teenager and failed to begin menstruating.

If the procedure works, Sara will have her own eggs fertilised using her boyfriend's sperm and then implanted into her donated womb.

Sara said she was unconcerned about the implications of receiving the womb that she was carried in.

''I haven't really thought about that,'' she said. ''I'm a biology teacher and it's just an organ like any other organ. But my mum did ask me about this. She said, 'Isn't it weird?' And my answer is no. I'm more worried that my mum is going to have a big operation.''

She added: ''It would mean the world to me for this to work and to have children.''

That could happen only a year after transplant.

Delivery would be a caesarean section, and the womb would then be removed.

Dr Mats Brannstrom, who is leading the medical team, said a womb transplant remained one of the most complex operations known to medical science.

''Technically, it is lot more difficult than transplanting a kidney, liver or heart,'' he said.

''The difficulty with it is avoiding haemorrhage and making sure you have long enough blood vessels to connect the womb. You are also working deep down in the pelvis area and it is like working in a funnel.''